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Practical recommendations for the management of diabetes in patients with COVID-19

Identifieur interne : 000018 ( France/Analysis ); précédent : 000017; suivant : 000019

Practical recommendations for the management of diabetes in patients with COVID-19

Auteurs : Stefan R. Bornstein [Allemagne, Royaume-Uni, Suisse] ; Francesco Rubino [Royaume-Uni] ; Kamlesh Khunti [Royaume-Uni] ; Geltrude Mingrone [Royaume-Uni, Italie] ; David Hopkins [Royaume-Uni] ; Andreas L. Birkenfeld [Royaume-Uni, Allemagne] ; Bernhard Boehm [Singapour] ; Stephanie Amiel [Royaume-Uni] ; Richard Ig Holt [Royaume-Uni] ; Jay S. Skyler [États-Unis] ; J Hans Devries [Pays-Bas, Allemagne] ; Eric Renard [France] ; Robert H. Eckel [États-Unis] ; Paul Zimmet [Australie] ; Kurt George Alberti [Royaume-Uni] ; Josep Vidal [Espagne] ; Bruno Geloneze [Brésil] ; Juliana C. Chan [République populaire de Chine] ; Linong Ji [République populaire de Chine] ; Barbara Ludwig [Allemagne, Suisse]

Source :

RBID : PMC:7180013

Abstract

Summary

Diabetes is one of the most important comorbidities linked to the severity of all three known human pathogenic coronavirus infections, including severe acute respiratory syndrome coronavirus 2. Patients with diabetes have an increased risk of severe complications including Adult Respiratory Distress Syndrome and multi-organ failure. Depending on the global region, 20–50% of patients in the coronavirus disease 2019 (COVID-19) pandemic had diabetes. Given the importance of the link between COVID-19 and diabetes, we have formed an international panel of experts in the field of diabetes and endocrinology to provide some guidance and practical recommendations for the management of diabetes during the pandemic. We aim to briefly provide insight into potential mechanistic links between the novel coronavirus infection and diabetes, present practical management recommendations, and elaborate on the differential needs of several patient groups.


Url:
DOI: 10.1016/S2213-8587(20)30152-2
PubMed: 32334646
PubMed Central: 7180013


Affiliations:


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Le document en format XML

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<name sortKey="Renard, Eric" sort="Renard, Eric" uniqKey="Renard E" first="Eric" last="Renard">Eric Renard</name>
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<name sortKey="Eckel, Robert H" sort="Eckel, Robert H" uniqKey="Eckel R" first="Robert H" last="Eckel">Robert H. Eckel</name>
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<region type="state">Colorado</region>
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<name sortKey="Zimmet, Paul" sort="Zimmet, Paul" uniqKey="Zimmet P" first="Paul" last="Zimmet">Paul Zimmet</name>
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<nlm:aff id="aff23">Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC, Australia</nlm:aff>
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</author>
<author>
<name sortKey="Alberti, Kurt George" sort="Alberti, Kurt George" uniqKey="Alberti K" first="Kurt George" last="Alberti">Kurt George Alberti</name>
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<name sortKey="Vidal, Josep" sort="Vidal, Josep" uniqKey="Vidal J" first="Josep" last="Vidal">Josep Vidal</name>
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<settlement type="city">Barcelone</settlement>
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<name sortKey="Geloneze, Bruno" sort="Geloneze, Bruno" uniqKey="Geloneze B" first="Bruno" last="Geloneze">Bruno Geloneze</name>
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<name sortKey="Chan, Juliana C" sort="Chan, Juliana C" uniqKey="Chan J" first="Juliana C" last="Chan">Juliana C. Chan</name>
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<nlm:aff id="aff27">Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
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<settlement type="city">Sha Tin</settlement>
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<name sortKey="Ji, Linong" sort="Ji, Linong" uniqKey="Ji L" first="Linong" last="Ji">Linong Ji</name>
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<wicri:regionArea>Department of Endocrinology and Metabolism, Peking University People's Hospital, Peking University Diabetes Center, Beijing</wicri:regionArea>
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<settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
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<name sortKey="Ludwig, Barbara" sort="Ludwig, Barbara" uniqKey="Ludwig B" first="Barbara" last="Ludwig">Barbara Ludwig</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany</nlm:aff>
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<wicri:regionArea>Department of Medicine III, University Hospital Carl Gustav Carus, Dresden</wicri:regionArea>
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<nlm:aff id="aff2">Paul Langerhans Institute Dresden of the Helmholtz Center Munich, University Hospital Carl Gustav Carus, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Paul Langerhans Institute Dresden of the Helmholtz Center Munich, University Hospital Carl Gustav Carus, Dresden</wicri:regionArea>
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<region type="land" nuts="1">Saxe (Land)</region>
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<settlement type="city">Dresde</settlement>
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<nlm:aff id="aff4">Department of Endocrinology and Diabetology, University Hospital Zurich, Zurich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Endocrinology and Diabetology, University Hospital Zurich, Zurich</wicri:regionArea>
<wicri:noRegion>Zurich</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff5">Faculty of Medicine, Technische Universität Dresden, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Faculty of Medicine, Technische Universität Dresden, Dresden</wicri:regionArea>
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<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
<orgName type="university">Université technique de Dresde</orgName>
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<nlm:aff id="aff6">Deutsche Forschungsgemeinschaft-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Deutsche Forschungsgemeinschaft-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Dresden</wicri:regionArea>
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<orgName type="university">Université technique de Dresde</orgName>
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<title xml:lang="en" level="a" type="main">Practical recommendations for the management of diabetes in patients with COVID-19</title>
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<name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R" last="Bornstein">Stefan R. Bornstein</name>
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<nlm:aff id="aff1">Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany</nlm:aff>
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<wicri:regionArea>Department of Medicine III, University Hospital Carl Gustav Carus, Dresden</wicri:regionArea>
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<country xml:lang="fr">Suisse</country>
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</placeName>
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<wicri:regionArea>German Center for Diabetes Research (DZD e.V.), Neuherberg</wicri:regionArea>
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<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
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<country xml:lang="fr">Royaume-Uni</country>
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<nlm:aff id="aff3">Department of Diabetes, School of Life Course Science and Medicine, King's College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Diabetes, School of Life Course Science and Medicine, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
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<settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
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<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Internal Medicine, Università Cattolica del Sacro Cuore, Rome</wicri:regionArea>
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<settlement type="city">Rome</settlement>
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</placeName>
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<name sortKey="Hopkins, David" sort="Hopkins, David" uniqKey="Hopkins D" first="David" last="Hopkins">David Hopkins</name>
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<nlm:aff id="aff3">Department of Diabetes, School of Life Course Science and Medicine, King's College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Diabetes, School of Life Course Science and Medicine, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
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<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Diabetes Endocrinology and Obesity, King's Health Partners, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Birkenfeld, Andreas L" sort="Birkenfeld, Andreas L" uniqKey="Birkenfeld A" first="Andreas L" last="Birkenfeld">Andreas L. Birkenfeld</name>
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<nlm:aff id="aff3">Department of Diabetes, School of Life Course Science and Medicine, King's College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Diabetes, School of Life Course Science and Medicine, King's College London, London</wicri:regionArea>
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<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research (DZD e.V.), Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Diabetology, Endocrinology and Nephrology, University Hospital Tübingen, Tübingen</wicri:regionArea>
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<region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
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</affiliation>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen</wicri:regionArea>
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<region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
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</affiliation>
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<author>
<name sortKey="Boehm, Bernhard" sort="Boehm, Bernhard" uniqKey="Boehm B" first="Bernhard" last="Boehm">Bernhard Boehm</name>
<affiliation wicri:level="1">
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<country xml:lang="fr">Singapour</country>
<wicri:regionArea>Department of Endocrinology, Tan Tock Seng Hospital, Singapore</wicri:regionArea>
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<affiliation wicri:level="1">
<nlm:aff id="aff16">Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea>Lee Kong Chian School of Medicine, Nanyang Technological University Singapore</wicri:regionArea>
<wicri:noRegion>Nanyang Technological University Singapore</wicri:noRegion>
</affiliation>
</author>
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<name sortKey="Amiel, Stephanie" sort="Amiel, Stephanie" uniqKey="Amiel S" first="Stephanie" last="Amiel">Stephanie Amiel</name>
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<nlm:aff id="aff3">Department of Diabetes, School of Life Course Science and Medicine, King's College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Diabetes, School of Life Course Science and Medicine, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Holt, Richard Ig" sort="Holt, Richard Ig" uniqKey="Holt R" first="Richard Ig" last="Holt">Richard Ig Holt</name>
<affiliation wicri:level="1">
<nlm:aff id="aff17">Human Development and Health, Faculty of Medicine, University of Southampton, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Human Development and Health, Faculty of Medicine, University of Southampton</wicri:regionArea>
<wicri:noRegion>University of Southampton</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Skyler, Jay S" sort="Skyler, Jay S" uniqKey="Skyler J" first="Jay S" last="Skyler">Jay S. Skyler</name>
<affiliation wicri:level="2">
<nlm:aff id="aff18">Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL</wicri:regionArea>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Devries, J Hans" sort="Devries, J Hans" uniqKey="Devries J" first="J Hans" last="Devries">J Hans Devries</name>
<affiliation wicri:level="3">
<nlm:aff id="aff19">Department of Endocrinology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Endocrinology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea>
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<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff20">Profil Institute for Metabolic Research, Neuss, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Profil Institute for Metabolic Research, Neuss</wicri:regionArea>
<wicri:noRegion>Neuss</wicri:noRegion>
<wicri:noRegion>Neuss</wicri:noRegion>
<wicri:noRegion>Neuss</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Renard, Eric" sort="Renard, Eric" uniqKey="Renard E" first="Eric" last="Renard">Eric Renard</name>
<affiliation wicri:level="3">
<nlm:aff id="aff21">Montpellier University Hospital and Institute of Functional Genomics, Centre national de la recherche scientifique, INSERM, University of Montpellier, Montpellier, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Montpellier University Hospital and Institute of Functional Genomics, Centre national de la recherche scientifique, INSERM, University of Montpellier, Montpellier</wicri:regionArea>
<placeName>
<region type="region">Occitanie (région administrative)</region>
<region type="old region">Languedoc-Roussillon</region>
<settlement type="city">Montpellier</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Eckel, Robert H" sort="Eckel, Robert H" uniqKey="Eckel R" first="Robert H" last="Eckel">Robert H. Eckel</name>
<affiliation wicri:level="2">
<nlm:aff id="aff22">Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO</wicri:regionArea>
<placeName>
<region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Zimmet, Paul" sort="Zimmet, Paul" uniqKey="Zimmet P" first="Paul" last="Zimmet">Paul Zimmet</name>
<affiliation wicri:level="1">
<nlm:aff id="aff23">Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC</wicri:regionArea>
<wicri:noRegion>VIC</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Alberti, Kurt George" sort="Alberti, Kurt George" uniqKey="Alberti K" first="Kurt George" last="Alberti">Kurt George Alberti</name>
<affiliation wicri:level="3">
<nlm:aff id="aff24">Division of Diabetes, Endocrinology and Metabolism, Imperial College, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Diabetes, Endocrinology and Metabolism, Imperial College, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Vidal, Josep" sort="Vidal, Josep" uniqKey="Vidal J" first="Josep" last="Vidal">Josep Vidal</name>
<affiliation wicri:level="3">
<nlm:aff id="aff25">Centro de Investigación Biomédica en Red en Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro de Investigación Biomédica en Red en Diabetes y Enfermedades Metabólicas Asociadas, Barcelona</wicri:regionArea>
<placeName>
<settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Geloneze, Bruno" sort="Geloneze, Bruno" uniqKey="Geloneze B" first="Bruno" last="Geloneze">Bruno Geloneze</name>
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<nlm:aff id="aff26">Obesity and Comorbities Research Center, Laboratory of Investigation in Metabolism and Diabetes/Gastrocentro, Universidade de Campinas, Campinas, São Paulo, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Obesity and Comorbities Research Center, Laboratory of Investigation in Metabolism and Diabetes/Gastrocentro, Universidade de Campinas, Campinas, São Paulo</wicri:regionArea>
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<settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Chan, Juliana C" sort="Chan, Juliana C" uniqKey="Chan J" first="Juliana C" last="Chan">Juliana C. Chan</name>
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<nlm:aff id="aff27">Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region</wicri:regionArea>
<orgName type="university">Université chinoise de Hong Kong</orgName>
<placeName>
<settlement type="city">Sha Tin</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ji, Linong" sort="Ji, Linong" uniqKey="Ji L" first="Linong" last="Ji">Linong Ji</name>
<affiliation wicri:level="3">
<nlm:aff id="aff28">Department of Endocrinology and Metabolism, Peking University People's Hospital, Peking University Diabetes Center, Beijing, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Endocrinology and Metabolism, Peking University People's Hospital, Peking University Diabetes Center, Beijing</wicri:regionArea>
<placeName>
<settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ludwig, Barbara" sort="Ludwig, Barbara" uniqKey="Ludwig B" first="Barbara" last="Ludwig">Barbara Ludwig</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medicine III, University Hospital Carl Gustav Carus, Dresden</wicri:regionArea>
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<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Paul Langerhans Institute Dresden of the Helmholtz Center Munich, University Hospital Carl Gustav Carus, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Paul Langerhans Institute Dresden of the Helmholtz Center Munich, University Hospital Carl Gustav Carus, Dresden</wicri:regionArea>
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<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
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<affiliation wicri:level="1">
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<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Endocrinology and Diabetology, University Hospital Zurich, Zurich</wicri:regionArea>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Faculty of Medicine, Technische Universität Dresden, Dresden</wicri:regionArea>
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<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
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<wicri:regionArea>Deutsche Forschungsgemeinschaft-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Dresden</wicri:regionArea>
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<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
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</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff7">German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research (DZD e.V.), Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series>
<title level="j">The Lancet. Diabetes & Endocrinology</title>
<idno type="ISSN">2213-8587</idno>
<idno type="eISSN">2213-8595</idno>
<imprint>
<date when="2020">2020</date>
</imprint>
</series>
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<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<title>Summary</title>
<p>Diabetes is one of the most important comorbidities linked to the severity of all three known human pathogenic coronavirus infections, including severe acute respiratory syndrome coronavirus 2. Patients with diabetes have an increased risk of severe complications including Adult Respiratory Distress Syndrome and multi-organ failure. Depending on the global region, 20–50% of patients in the coronavirus disease 2019 (COVID-19) pandemic had diabetes. Given the importance of the link between COVID-19 and diabetes, we have formed an international panel of experts in the field of diabetes and endocrinology to provide some guidance and practical recommendations for the management of diabetes during the pandemic. We aim to briefly provide insight into potential mechanistic links between the novel coronavirus infection and diabetes, present practical management recommendations, and elaborate on the differential needs of several patient groups.</p>
</div>
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<affiliations>
<list>
<country>
<li>Allemagne</li>
<li>Australie</li>
<li>Brésil</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>République populaire de Chine</li>
<li>Singapour</li>
<li>Suisse</li>
<li>États-Unis</li>
</country>
<region>
<li>Angleterre</li>
<li>Bade-Wurtemberg</li>
<li>Catalogne</li>
<li>Colorado</li>
<li>District de Dresde</li>
<li>District de Tübingen</li>
<li>Floride</li>
<li>Grand Londres</li>
<li>Hollande-Septentrionale</li>
<li>Languedoc-Roussillon</li>
<li>Latium</li>
<li>Occitanie (région administrative)</li>
<li>Saxe (Land)</li>
<li>État de São Paulo</li>
</region>
<settlement>
<li>Amsterdam</li>
<li>Barcelone</li>
<li>Dresde</li>
<li>Londres</li>
<li>Montpellier</li>
<li>Pékin</li>
<li>Rome</li>
<li>Sha Tin</li>
<li>São Paulo</li>
<li>Tübingen</li>
</settlement>
<orgName>
<li>Université chinoise de Hong Kong</li>
<li>Université technique de Dresde</li>
</orgName>
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<region name="Saxe (Land)">
<name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R" last="Bornstein">Stefan R. Bornstein</name>
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<name sortKey="Birkenfeld, Andreas L" sort="Birkenfeld, Andreas L" uniqKey="Birkenfeld A" first="Andreas L" last="Birkenfeld">Andreas L. Birkenfeld</name>
<name sortKey="Birkenfeld, Andreas L" sort="Birkenfeld, Andreas L" uniqKey="Birkenfeld A" first="Andreas L" last="Birkenfeld">Andreas L. Birkenfeld</name>
<name sortKey="Birkenfeld, Andreas L" sort="Birkenfeld, Andreas L" uniqKey="Birkenfeld A" first="Andreas L" last="Birkenfeld">Andreas L. Birkenfeld</name>
<name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R" last="Bornstein">Stefan R. Bornstein</name>
<name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R" last="Bornstein">Stefan R. Bornstein</name>
<name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R" last="Bornstein">Stefan R. Bornstein</name>
<name sortKey="Devries, J Hans" sort="Devries, J Hans" uniqKey="Devries J" first="J Hans" last="Devries">J Hans Devries</name>
<name sortKey="Ludwig, Barbara" sort="Ludwig, Barbara" uniqKey="Ludwig B" first="Barbara" last="Ludwig">Barbara Ludwig</name>
<name sortKey="Ludwig, Barbara" sort="Ludwig, Barbara" uniqKey="Ludwig B" first="Barbara" last="Ludwig">Barbara Ludwig</name>
<name sortKey="Ludwig, Barbara" sort="Ludwig, Barbara" uniqKey="Ludwig B" first="Barbara" last="Ludwig">Barbara Ludwig</name>
<name sortKey="Ludwig, Barbara" sort="Ludwig, Barbara" uniqKey="Ludwig B" first="Barbara" last="Ludwig">Barbara Ludwig</name>
<name sortKey="Ludwig, Barbara" sort="Ludwig, Barbara" uniqKey="Ludwig B" first="Barbara" last="Ludwig">Barbara Ludwig</name>
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<name sortKey="Birkenfeld, Andreas L" sort="Birkenfeld, Andreas L" uniqKey="Birkenfeld A" first="Andreas L" last="Birkenfeld">Andreas L. Birkenfeld</name>
<name sortKey="Holt, Richard Ig" sort="Holt, Richard Ig" uniqKey="Holt R" first="Richard Ig" last="Holt">Richard Ig Holt</name>
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<name sortKey="Skyler, Jay S" sort="Skyler, Jay S" uniqKey="Skyler J" first="Jay S" last="Skyler">Jay S. Skyler</name>
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<name sortKey="Eckel, Robert H" sort="Eckel, Robert H" uniqKey="Eckel R" first="Robert H" last="Eckel">Robert H. Eckel</name>
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<region name="Hollande-Septentrionale">
<name sortKey="Devries, J Hans" sort="Devries, J Hans" uniqKey="Devries J" first="J Hans" last="Devries">J Hans Devries</name>
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<name sortKey="Renard, Eric" sort="Renard, Eric" uniqKey="Renard E" first="Eric" last="Renard">Eric Renard</name>
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<name sortKey="Vidal, Josep" sort="Vidal, Josep" uniqKey="Vidal J" first="Josep" last="Vidal">Josep Vidal</name>
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<region name="État de São Paulo">
<name sortKey="Geloneze, Bruno" sort="Geloneze, Bruno" uniqKey="Geloneze B" first="Bruno" last="Geloneze">Bruno Geloneze</name>
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</country>
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</affiliations>
</record>

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